After reading a few threads where people don't have the foggiest clue how to extract things from plants or how to purify dirty drugs, I figured I'd post the basics for the benefit of noobs. Keep in mind I have very little chemistry learnings, so pls feel free to correct me if you know better.Most drugs belong to a family of molecules called alkaloids. This is a pretty handy thing to know, since they all have similar chemical properties and behave more or less the same way, Examples of drugs that are alkaloids include: cocaine, heroin, morphine, codeine, lsd, dmt, mescaline, psilocybin, dxm, etc etc. Drugs that are not alkaloids are very few, and they include THC and Salvinorin A. Comment too long. Click here to view the full text.
After reading a few threads where people don't have the foggiest clue how to extract things from plants or how to purify dirty drugs, I figured I'd post the basics for the benefit of noobs. Keep in mind I have very little chemistry learnings, so pls feel free to correct me if you know better.
Most drugs belong to a family of molecules called alkaloids. This is a pretty handy thing to know, since they all have similar chemical properties and behave more or less the same way, Examples of drugs that are alkaloids include: cocaine, heroin, morphine, codeine, lsd, dmt, mescaline, psilocybin, dxm, etc etc. Drugs that are not alkaloids are very few, and they include THC and Salvinorin A.
>>9843I lol'd
>>9843
I lol'd
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DMT is pretty basic fucking chemistry to extract...acid/base extraction and defat, repeat, recrystalize until your crystals are the desired purity, they will probably start yellow, then you might get some clear crystals...
DMT is pretty basic fucking chemistry to extract...
acid/base extraction and defat, repeat, recrystalize until your crystals are the desired purity, they will probably start yellow, then you might get some clear crystals...
sup /chem/, fag here looking to extract using fresh (NOT dried) shrooms, anyone care to comment?get fresh shrooms, washgooify in blenderimmediately toss into boiling, thus deoxygenated water to denature/destroy destructive enzymes, leave for 5 mins? then remove from heatonce cooled to ~150 degrees, add enough ethanol/methanol to make a 70:30 alcohol:water-shroom-gunk mixstir periodically for 10 hours, filter, evaporate, store remaining gunk with desiccant Comment too long. Click here to view the full text.
sup /chem/, fag here looking to extract using fresh (NOT dried) shrooms, anyone care to comment?
>>11324Jab, I think.
>>11324
Jab, I think.
i think i didn't communciate my goal well. starting with fresh shrooms, a stable compact extraction is desired in as short a time as possible. gunk is acceptable, extra time is not. psilocybin is wanted, psilocin/baeocystin both decay so are irrelevant.most extractions allow aqueous phosphatase to convert desired psilocybin to undesired psilocin. this can be avoided with pure methanol and dried shrooms, which is not possible here (time).the idea is that you expose fresh shrooms to very high heat to denature phosphatase asap, rendering it inert, allowing high-heat (thus fast) extraction into water/alcohol without having to worry about dephosphorylation of psilocybin. Comment too long. Click here to view the full text.
i think i didn't communciate my goal well. starting with fresh shrooms, a stable compact extraction is desired in as short a time as possible. gunk is acceptable, extra time is not. psilocybin is wanted, psilocin/baeocystin both decay so are irrelevant.
most extractions allow aqueous phosphatase to convert desired psilocybin to undesired psilocin. this can be avoided with pure methanol and dried shrooms, which is not possible here (time).
the idea is that you expose fresh shrooms to very high heat to denature phosphatase asap, rendering it inert, allowing high-heat (thus fast) extraction into water/alcohol without having to worry about dephosphorylation of psilocybin.
above about 60C (140F) pretty much all the enzymes are going to be denatured, but while you're blenderizing the mushrooms, they're going to be at room temperature, so you might want to freeze them first. i realize this adds unwanted extra time to your recipe; maybe flash-freeze them with keyboard duster? freezing stops protein action dead, and might even help your extraction down the line (busted cell membranes)
I've been wondering to myself.. Is it possible, /chem/ through the use of plastic surgery, is it possible to give oneself a different 'race'? eg...white to asian?inb4/weeaboo
I've been wondering to myself.. Is it possible, /chem/ through the use of plastic surgery, is it possible to give oneself a different 'race'? eg...white to asian?
inb4/weeaboo
are we forgetting the obvious? MJ?
very possible, skin bleaching is done all the time and i'm pretty sure there is a name for giving yourself mooninite eyes
google "Chlorinol" and "de white negro"
Why does no one ever synth DMT from tryptamine via an Eschweiler-Clarke reaction? Is there some contraindication that I'm not aware of? I came across it in my Ochem book, and it seems like it'd be cheaper and cleaner than the MHRB route that's all the rage, plus it can be done single pot. Is tryptamine watched or something?I should note I have access both formalin and formaldehyde.
Why does no one ever synth DMT from tryptamine via an Eschweiler-Clarke reaction? Is there some contraindication that I'm not aware of? I came across it in my Ochem book, and it seems like it'd be cheaper and cleaner than the MHRB route that's all the rage, plus it can be done single pot. Is tryptamine watched or something?
I should note I have access both formalin and formaldehyde.
>>11326Curious, wiki (i dunno the source) lines up really close with what I got. perhaps coincidental.
>>11326
Curious, wiki (i dunno the source) lines up really close with what I got. perhaps coincidental.
EMPHASIS FOR PEOPLE JUST COMING TO THE THREAD NOWThere is a chance tryptoline (which is highly likely to be a significant byproduct) could be dangerously neurotoxic. Those who follow this synth and consume the product (which they should not do if it is illegal in the jurisdiction wherein they reside) accept full responsibility for the possibilty of permanent side affects.END DISCLAIMER Comment too long. Click here to view the full text.
EMPHASIS FOR PEOPLE JUST COMING TO THE THREAD NOW
There is a chance tryptoline (which is highly likely to be a significant byproduct) could be dangerously neurotoxic. Those who follow this synth and consume the product (which they should not do if it is illegal in the jurisdiction wherein they reside) accept full responsibility for the possibilty of permanent side affects.
END DISCLAIMER
Some of the beta carbolines are potential neurotoxins. However, according to the wiki on beta-carbolines, tryptoline is naturally produced within the brain. http://en.wikipedia.org/wiki/Beta-carbolineAlthough not concrete fact, logic would seem to dictate that the brain would not produce something that is toxic to itself.
Some of the beta carbolines are potential neurotoxins. However, according to the wiki on beta-carbolines, tryptoline is naturally produced within the brain. http://en.wikipedia.org/wiki/Beta-carboline
Although not concrete fact, logic would seem to dictate that the brain would not produce something that is toxic to itself.
Salutations, /chem/. School starts soon and I need some ideas on what to do as my independent research project required for a master's degree. I was hoping you all could help me brainstorm.I'm interested in industrial/agricultural chemistry. My topic needs to be oddly specific or else its just a "repost of a repost of a..." so I began thinking and I realized how much I like the desert and Mary J. both. So what kind of research needs to be done chemically in the desert, if any? This is just one idea but I will keep thinking on it and try to come back with more. Any help is welcome and I will try to keep contributing my thoughts so not to make you all do my work for me. Comment too long. Click here to view the full text.
Salutations, /chem/. School starts soon and I need some ideas on what to do as my independent research project required for a master's degree. I was hoping you all could help me brainstorm.
I'm interested in industrial/agricultural chemistry. My topic needs to be oddly specific or else its just a "repost of a repost of a..." so I began thinking and I realized how much I like the desert and Mary J. both.
So what kind of research needs to be done chemically in the desert, if any? This is just one idea but I will keep thinking on it and try to come back with more. Any help is welcome and I will try to keep contributing my thoughts so not to make you all do my work for me.
get some random desert plant to start producing cannabinoidssum gui named alfred nanofsky did this a while back with orange trees. no one knows if those oranges are illegal, but they'll get you high as fuck and should be circulating pretty soon. it took him 14 years or someshit to isolate the gene and splice it into oranges. look this bad boy up for sum tips
>>11307I think that orange story is a fake, although it would be epic if I could do something like that. Only thing is, that gets into bioengineering and genetic modification, some things I don't intend to study.>>11274Cleaner pesticides would be something I could research. I'd have to do a literature review on it first to see what's all ready been done and find a question about it that hasn't been asked yet. Do they use many pesticides in the desert anyway? Comment too long. Click here to view the full text.
>>11307
I think that orange story is a fake, although it would be epic if I could do something like that. Only thing is, that gets into bioengineering and genetic modification, some things I don't intend to study.
>>11274
Cleaner pesticides would be something I could research. I'd have to do a literature review on it first to see what's all ready been done and find a question about it that hasn't been asked yet. Do they use many pesticides in the desert anyway?
>>11319As an entomology major, I would not suggest researching insects and farm pesticides, unless you have a seriously good question to ask. The field is obviously gigantic and most of what can be thought of has already been tested.
Hi /chem/.My great uncle died due to the effects of lung cancer yesterday, he was 83 years old. Before his death he claimed to have lived a long and fulfilling life, so he didn't bother with chemotherapy.Now, I've recently come to understand that instead of getting a proper burial or cremation, he has donated his body to science.I have no idea what this is supposed to mean; it's all very unfamiliar to me.My question to you is: where will his remains end up and what's going to happen to them?
>>11312they will use everything they can, either as a whole cadaver for surgery/whatever practice or split him up for organ study n shit like thatincinerate him or some shityeah, shit like that
since he had lung cancer his body is probably going to be used in an anti smoking commercial
all of the above minus the dog food.
In the near future I plan on doing a DMT extraction. I was just wondering if there's any consensus on the 'best' tek to do this with. Someone recommended QT's extraction for students, but to be honest I don't want to have an extraction setup persisting in my kitchen for a month.I value purity over yield any day. Is there anything you guys recommend?
In the near future I plan on doing a DMT extraction. I was just wondering if there's any consensus on the 'best' tek to do this with. Someone recommended QT's extraction for students, but to be honest I don't want to have an extraction setup persisting in my kitchen for a month.
I value purity over yield any day. Is there anything you guys recommend?
standard straight to base, cleaning it up afterwards is really easy generally if it's purity isn't good enough for you
Best advice for you is to LEARN the chemistry behind the recipe. Don't just follow directions, unless you will be just like all the fucking meth cooks out there who ruin the hobby for the rest of us...
>>11302That was good advice. I don't have any sort of chem background so it probably took me longer than normal to try and absorb the information... Correct me if I'm wrong on anything, but this is my understanding of the principles involved;An acid plus an alkaloid yields a salt, which is water soluble, but not soluble in nonpolar solvents. A base plus an alkaloid yields a freebase which is not soluble in water, but is soluble in a nonpolar solvent. Comment too long. Click here to view the full text.
>>11302
That was good advice. I don't have any sort of chem background so it probably took me longer than normal to try and absorb the information... Correct me if I'm wrong on anything, but this is my understanding of the principles involved;
An acid plus an alkaloid yields a salt, which is water soluble, but not soluble in nonpolar solvents. A base plus an alkaloid yields a freebase which is not soluble in water, but is soluble in a nonpolar solvent.
how does surface tenson affect the functioning of a living organism, /chem/?
it affects everything with everything.
http://www.rathergood.com/zoology/
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